CamAPS HX for T2D (mg/dL)

Disclaimer

This app is intended to assist with managing your diabetes and should not be used as a substitute for professional medical advice.

Key Functionality

The CamAPS HX app connects to a continuous glucose sensor, processes the sensor data and instructs the amount of insulin to be administered by an insulin pump in a glucose responsive fashion.

No information about meals is required and insulin boluses are not needed at meal time. This is known as “fully” closed-loop or “fully” automated insulin delivery.

The CamAPS HX app allows data upload to the cloud for data visualisation.

Modes of Operation

The CamAPS HX app operates in one of two modes:

(1) Auto mode Off (open loop)
Auto mode Off is the mode of operation most familiar to current pump users. In this mode of operation, the pump operates at the pre-programmed basal profile, or as instructed by the user. The communication with the CGM is maintained and the sensor glucose information is displayed.

Auto mode Off is the default mode of operation on system start-up.

(2) Auto mode On (closed loop)
Auto mode or closed loop mode is the mode of operation where:

a) Insulin delivery is directed by the app replacing pre-programmed basal insulin delivery.
or
b) The ‘app’ is attempting to enter Auto mode but a condition is preventing it from doing so, for example, when CGM data become unavailable. The ‘attempting’ status continues until the condition preventing the start of Auto mode is resolved. When in ‘attempting’ mode, insulin infusion will revert to the pre-programmed basal rate after approximately 30 minutes.

How closed-loop work?

The CamAPS HX app uses a mathematical model of insulin action to determine insulin infusion leading to a target glucose of around 105mg/dL.

For the model of insulin action to operate correctly, information is needed at setup and then during the system operation. The body weight is used to approximate glucose and insulin concentrations within the body. The total daily dose of insulin is an initial indicator of insulin sensitivity, which is further refined by analysing continuous glucose monitor (CGM) data, previously administered insulin infusion and boluses, and meal intake.

Previous insulin infusion and boluses, together with CGM and meal data are used to update insulin sensitivity and other subject specific characteristics. The mathematical model then uses these characteristics together with information about active insulin and active meals to predict future glucose concentrations and to determine the optimum insulin infusion leading to the target glucose level.

In certain situations such as when CGM glucose is low or is decreasing fast, the control algorithm may further reduce insulin to reduce the risk of hypoglycaemia.

Instructions for use are available in electronic format via the app. PDF viewer is required to read the electronic instructions. For a paper copy of instructions, please contact support@camdiab.com.