Dionysus Digital Health

The Enlighten Mood Tracker is a new approach for maximizing health and wellness that combines the power of AI with innovative digital and biological insights. We empower our users to take control of their mental health, and to make personalized care accessible, engaging, and effective for all.

Our App provides personalized support, via delivery of smart digital interventions optimized for you based on the perceived stress and anxiety you are experiencing in real life. Powered by a suite of powerful algorithms that reveal the patterns of stress in your life, we can help you understand the underlying causes based on your unique experiences and biology. More than simply a wearable based stress score, we help you understand the “why?” and provide scientifically validated approaches to directly address it.

If the system identifies patterns of stress that suggest hormonal sensitivity, we can recommend our biomarker test to help understand your unique epigenetic signature. Based on your environmental exposures throughout your life, epigenetics opens the door to understand your biological sensitivity to hormone levels. Through our clinical partners we provide the opportunity to access precision medical interventions optimized to specific biology.

Our custom epigenetic chip “Enlighten” comprises a proprietary set of biomarkers for identifying an individual’s inherent biological susceptibility to hormone sensitivity, including the ability to predict, and prevent important female associated mood disorders associated with postpartum depression, PMS and perimenopausal depression.

The term “Epigenetics” literally means over your genes, and epigenetic changes underlie important biological changes which are triggered by your environment. For example, they explain why your skin darkens after exposure to sunlight, and why the genes expressed in your brain are different than those expressed in your liver. Epigenetic profiles can therefore help you understand how your environment – what you eat, your exposure to environmental toxins, and your lifestyle – has impacted your genes. Based on research over the last decade we can use this information to provide specific insights about how these changes can affect your health and wellness. Critically, we use this information to help you take control of your mental health and wellness using scientifically validated approaches based on your personalized epigenetic signature.

To do this, the Enlighten test provides actionable insights on your epigenetic exposure scores across 4 core domains:
1. Lifestyle modifiable factors, including exercise, alcohol intake, smoking, folic acid, vitamin K, & omega fatty acid exposure scores.
2. Toxic Exposures, such as potentially toxic or teratogenic environmental exposures such as lead, mercury, diesel exhaust, zinc, & smoking exposure.
3. Hormonal Sensitivity including those related to epigenetic changes associated with FSH, progesterone, allopregnanolone, estradiol and hormonal sensitivity to stress.
4. Healthy aging including epigenetic patterns associated with healthy aging - including Alzheimer’s disease risk, biological age, inflammation, estimated time to menopause, and susceptibility to perimenopausal depression.

Scientific Validation
In 2013, our co-founders published the first identification of a panel of epigenetic biomarkers prospectively predictive of hormonal sensitivity associated with postpartum depression risk with 80% accuracy when sampled in third trimester blood. We have since replicated this finding in 6 additional cohorts and are aware of an independent replication. More recently, our scientists have expanded these studies to other forms of hormonal sensitivity including mood disorders associated with PMS, and its more severe clinicals forms, as well as depressions and mood disorders associated with menopause. Critically we can also determine the appropriate type of medications which will be most appropriate to you.