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The United States Medical Licensing Examination ® (USMLE®) is a three-step examination for medical licensure in the United States and is sponsored by the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners® (NBME®).

The USMLE assesses a physician's ability to apply knowledge, concepts, and principles, and to demonstrate fundamental patient-centered skills, that are important in health and disease and that constitute the basis of safe and effective patient care. Each of the three Steps of the USMLE complements the others; no Step can stand alone in the assessment of readiness for medical licensure.
Step 1

USMLE Step 1 assesses whether medical school students or graduates understand and can apply important concepts of the basic sciences to the practice of medicine. As of 2007, it covers the following subjects, in both systemic (general and individual anatomical characteristics) and procedural (functional, therapeutic, environmental, and abnormality) themes:

Pathology,
Pharmacology,
Physiology,
Microbiology,
Biochemistry,
Anatomy,
Behavioral sciences,

Interdisciplinary topics, such as nutrition, genetics, and aging.

US medical students take Step 1 at the end of the Basic Sciences portion of the curriculum, usually after the second year of medical school.

The Step 1 score is frequently used in medical residency applications as a measure of a candidate's likelihood to succeed in that particular residency (and on that specialty's board exams).


Step 2

USMLE Step 2 is designed to assess whether medical school students or graduates can apply medical knowledge.
Step 2-CK

USMLE Step 2 CK is designed to assess clinical knowledge through a traditional, multiple-choice examination. It is a 9 hour exam
Step 2-CS

USMLE Step 2 CS is designed to assess clinical skills through simulated patient interactions, in which the examinee interacts with standardized patients portrayed by actors.

USMLE Step 3 is the final exam in the USMLE series designed to assess whether a medical school graduate can apply medical knowledge and understanding of biomedical and clinical science essential for the unsupervised practice of medicine.


In other countries

Medical Council of Canada Qualifying Examination, in Canada
Professional and Linguistic Assessment Board test (similar exam used in United Kingdom)
Australian Medical Council (AMC) in Australia.
Medical Council of India (MCI-FMGE conducted by National Board of Examinations)
Examen Nacional de Aspirantes a Residencias Medicas (ENARM) in Mexico.
Ärztliche Prüfungen, overseen by the IMPP, in Germany.